Star Polymers: An Overview

DOI:

https://doi.org/10.37285/ijpsn.2012.5.2.3

Authors

  • Rohini Anandrao Patil
  • N H Aloorkar
  • A S Kulkarni
  • D J Ingale

Abstract

This review article describes the synthesis, properties and some applications of star-shaped polymers. The arms constituted of homo- or co-polymers of different polymers are also reviewed. Methods of synthesis of various types of star-shaped polymers, including “arm first” and “core first” procedures,  is given as an introduction along with some details. Then, the synthesis of star polymers (including miktoarm stars) with strictly defined as well as with varying number of arms and having cores formed from small and/or large molecules: branched, cross-linked, etc., is described. Interest in star-shaped and branched systems based on poly (ethylene oxide) (PEO) is mainly motivated by their potential applications in the biomedical and pharmaceutical areas. The properties and applications of PEO stars are also reported, such as drug carriers, surface modifiers, hydrogels, components of membranes, and also have some biomedical applications. Their potential applications as components of different types of complexes, hydrogels, networks, and ultrathin coatings are indicated. 

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Keywords:

Star polymers, miktoarm star polymers, poly (ethylene oxide) stars, core first, arm first, drug carrier, interpenetrating polymeric networks.

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Published

2012-08-31

How to Cite

1.
Patil RA, Aloorkar NH, Kulkarni AS, Ingale DJ. Star Polymers: An Overview. Scopus Indexed [Internet]. 2012 Aug. 31 [cited 2024 Dec. 11];5(2):1675-84. Available from: https://www.ijpsnonline.com/index.php/ijpsn/article/view/571

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Section

Review Articles

References

Angot, S.; Murthy, K. S.; Taton, D.; Gnanou, Y (1998). Macromolecules 31:7218-7225

Bywater S (1979). Preparation and properties of star-branched polymers. Adv Polym Sci 30:89–116.

Carnahan MA, Middleton C, Kim J, Kim T, Grinstaff MW (2002). Hybrid dendritic-linear polyester–ethers for in situ photopolymerization. J Am Chem Soc 124:5291–3.

Dalton PD, Hostert C, Albrecht K, Moeller M, Groll J (2008). Structure and properties of urea-crosslinked star poly[(ethylene oxide)-ran-(propylene oxide)] hydrogels. Macromol Biosci 8:923–31.

Griffith-Cima L, Lopina ST (1995). Network structures of radiation-crosslinked star polymer gels. Macromolecules 28:6787–94.

Groll J, Ademovic Z, Ameringer T, Klee D, Moeller M (2005). Comparison of coatings from reactive star shaped PEG-stat-PPG prepolymers and grafted linear PEG for biological and medical applications. Biomacromolecules 6:956–62.

Grzegorz Lapienis (2009). Star-shaped polymers having PEO arms. Progress in Polymer Science 34: 852–892.

H.A.M. van Aert, M.H.P. Van genderen, E W Meijer (1996). Star-shaped poly 2,6 Dimethyl- 1,4-phenylene ether), Polymer Bulletin 37:273-280.

Harris JM, Zaplisky S, editors (1997). Poly(ethylene glycol): chemistry and biomedical applications. ACS Symposium Series 680. Washington, DC: Am Chem Soc; 1997.

Held D, Müller AHE (2000). Synthesis and solution properties of star-shaped poly(tert-butyl acrylate). Macromol Symp 157:225–37.

Jie P, Venkatraman SS, Min F, Freddy BYCh, Huat GL (2005). Micelle-like nanoparticles of star-branched PEO–PLA copolymers as chemotherapeutic carrier. J Control Rel 110: 20-33.

Keys KB, Andreopoulos FM, Peppas NA (1998). Poly (ethylene glycol) star polymer hydrogels. Macromolecules 31: 8149–56.

Knischka R, Lutz PJ, Sunder A, Frey H (2001). Structured hydrogels based on poly (ethyleneoxide) multi-arm stars with hyperbranched polyglycerol. Polym Mater Sci Eng 84: 945–946.

Knischka R, Lutz PJ, Sunder A, Mülhaupt R, Frey H (2000). Functional poly(ethylene oxide) multiarm star polymers: core-first synthesis using hyperbranched polyglycerol initiators. Macromolecules 33: 315–320.

Kojima Ch, Kono K, Maruyama K, Takagishi T (2000). Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs. Bioconj Chem 11:910–7.

Lapienis G, Penczek S (2004). Reaction of oligoalcohols with diepoxides: an easy, one-pot way to star-shaped, multibranched polymers. II. Poly(ethylene oxide) stars—synthesis and analysis by size exclusion chromatography triple-detection method. J Polym Sci Part A: Polym Chem 42:1576–98, 2575–6.

Lapienis G (2009). Functionalized star-shaped polymers having PEO and/or polyglycidyl arms and their properties. Polymer 50:77–84.

Lutolf MP, Lauer-Fields JL, Schmoekel HG, Metters AT, Weber FE, Fields GB (2003). Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. PNAS 100:5413–8.

Merrill EW (1993). Poly(ethylene oxide) star molecules: synthesis, characterization,and applications in medicine and biology. J Biomater Sci Polym Ed 5:1–11.

Miao J, Xu G, Zhu L, Tian L, Uhrich KE, Avila-Orta CA (2005). Chainfolding and overall molecular conformation in a novel amphiphilic starlike macromolecule. Macromolecules 38:7074–82.

Roovers J and Comanita B (1999). Dendrimers and dendrimer-polymer hybrids. Adv Polym Sci 142:179–228 24.

Steege KE, Wang J, Uhrich KE, Castner Jr EW (2007). Local polarity and microviscosity in the hydrophobic cores ofamphiphilic star-like and scorpion-like macromolecules. Macromolecules 40:3739–48.

Sukumar VS and Lopina ST (2002). Network model for the swelling properties of end-linked linear and star poly (ethylene oxide) hydrogels. Macromolecules 35:10189–92.

Wódzki R, S´wia˛tkowski M, Łapienis G (2002). Properties of star-shaped polymer with poly (oxyethylene) branches and monoesters of phosphoric acid end groups in pertraction of alkali, alkaline earth, and transient metal cations. React Funct Polym 52:149–61.

Xia J, Zhang, X and Matyjaszewski K (1999). Macromolecules 32:4482-4484.

Xie H and Xia J (1987) Synthesis and properties of star shaped block copolymers of styrene and ethylene oxide. Makromol Chem 188:2543–2552

Yen DR and Merrill EW (1997). Synthesis of PEO star molecules based on PAMAM dendrimer cores. Polymer Prepr Am Chem Soc Div Polym Chem 38: 531–532.

Yin Y, Yang L, Yoshino M, Fang J, Tanaka K, Kita H (2004). Synthesis and gas permeation properties of star-like poly(ethylene oxide)s using hyperbranched polyimide as central core. Polym J 36:294–302.

Zimm BH and Stockmayer WH (1949). The dimentions of chain molecules containing branches and rings. J Chem Phys 17:1301–1314.