Drug Utilization Evaluation of Anti-Hypertensive Drugs in a Tertiary Care Teaching Hospital: An Observational Study

DOI:

https://doi.org/10.37285/ijpsn.2024.17.2.8

Authors

Abstract

Background: Hypertension is a condition causing increased circulatory strain, with Systolic blood pressure (SBP) and diastolic blood pressure (DBP) reaching 140mmHg and 90mmHg, respectively. Drug utilization evaluation (DUE) is a systematic process for quantifying, understanding, and analyzing prescribing, dispensing, and medication utilization.

Aims: To Assess Drug Utilization Evaluation of Anti-Hypertensive Drugs in A Tertiary Care Teaching Hospital

Methods: A prospective observational study was conducted, 200 subjects were included from the inpatient department for over a period of six months as per the inclusion and exclusion criteria. The proper descriptive statistical analysis was used to statistically analyze the acquired data.

Results: Out of 200 subjects, 64% were male and 36% were female. Monotherapy was widely prescribed for Hypertensive patients. In the study, the most prescribed class of drug was calcium channel blocker (amlodipine), followed by calcium channel blocker+ diuretics and calcium channel blocker +beta blocker + diuretics in combination therapy.

Conclusions: In this article, we conclude that Amlodipine is the most prescribed drug, the most widely prescribed drug class was calcium channel blockers followed by Angiotensin-converting enzyme inhibitor.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Keywords:

Hypertension, DrugUtilizationEvaluation, AntihypertensiveDrugs

Published

2024-03-31

How to Cite

1.
HIREMATH J, Nyamagoud SB, Swamy V, SHUKLA S, HIREMATH N, SARKAR A, et al. Drug Utilization Evaluation of Anti-Hypertensive Drugs in a Tertiary Care Teaching Hospital: An Observational Study. Scopus Indexed [Internet]. 2024 Mar. 31 [cited 2024 Oct. 11];17(2):7270-6. Available from: https://www.ijpsnonline.com/index.php/ijpsn/article/view/4298

Issue

Section

Research Articles

References

Mahmood S, Jalal Z, Hadi A, Orooj M, Shah H. Non-Adherence to Prescribed Antihypertensives in Primary, Secondary and Tertiary Healthcare Settings in Islamabad, Pakistan: A Cross-Sectional Study&lt. 2020 Jan 14;14:73-85.

Datta S. Utilization study of antihypertensives in a south Indian tertiary care teaching hospital and adherence to standard treatment guidelines. J Basic Clin Pharm. 2016;8(1):33–7. Available from: http://dx.doi.org/10.4103/0976-0105.195100

Paul GK, Karmoker KK, Sen B, Hussain MZ, Hasan MS, Khan MK. Risk Factors for Hypertension in Young Adults of Bangladesh. Mymensingh Med J. 2020;29(1):43-47.

Goodhart AK. Hypertension from the patient’s perspective. Br J Gen Pract. 2016;66(652):570–570. Available from: http://dx.doi.org/10.3399/bjgp16x687757

Bergman U. The history of the Drug Utilization Research Group in Europe. Pharmacoepidemiol Drug Saf. 2006;15(2):95–8. Available from: http://dx.doi.org/10.1002/pds.1171

Sluss PM. Utilization management initiatives that can be imported into healthcare systems. In: Utilization Management in the Clinical Laboratory and Other Ancillary Services. Cham: Springer International Publishing; 2017. p. 287–90.

Sharma A. Drug utilization study on hypertensive patients and assessment of medication adherence to jnc-8 guidelines in north Indian tertiary care hospital: A cross-sectional study. Adv Res Gastroenterol Hepatol. 2018;9(1). Available from: http://dx.doi.org/10.19080/argh.2018.09.555751

Afanasjeva J, Burk M, Cunningham FF, Fanikos J, Gabay M, Hayes GJ, et al. ASHP guidelines on medication-use evaluation. Am J Health Syst Pharm. 2021;78(2):168–75. Available from:

http://dx.doi.org/10.1093/ajhp/zxaa393

Gangwar R, Kumar A, Zargar AA, Sharma A, Kumar R. The role of drug utilization evaluation in medical sciences. Glob Health J. 2023;7(1):3–8. Available from: http://dx.doi.org/10.1016/j.glohj.2023.02.002

Vp A, Muhas, Sruthy S A. Drug utilization pattern of antihypertensive medications in a tertiary care hospital, south India. Asian J Pharm Clin Res. 2021;115–8.

Mankadavath A, Chandrasekhar D, Thomas T, Zuhra F, Kaipanthodi S, Parambil JC. A prospective drug use evaluation of antihypertensive drugs in in-patients of a tertiary referral care hospital. J Basic Clin Physiol Pharmacol. 2015;26(3):295–300. Available from: http://dx.doi.org/10.1515/jbcpp-2013-0131

Ramadas S, Sujatha MB, Andrews MA, K. B. S. Drug utilization study of antihypertensive drugs and prevalence of blood pressure control in adult hypertensive patients based on JNC VIII guidelines in a tertiary care hospital: a cross sectional study. Int J Basic Clin Pharmacol [Internet]. 2019;8(2):245. Available from: http://dx.doi.org/10.18203/2319-2003.ijbcp20190142

Eslampanah Z. Drug Utilization Evaluation of Anti-Hypertensive Agents in A Medical Care Hospital. International Journal of Pharmaceutical Sciences and Research. 2016.(7)