Ocimum Sanctum: A Herbal Agent for Revivification of Periodontal Health

DOI:

https://doi.org/10.37285/ijpsn.2023.16.2.7

Authors

  • Vanshika Agarwal Department of Periodontology, School of Dental Sciences, Sharda University
  • Ansuiya Warikoo Department of Periodontology, School of Dental Sciences, Sharda University
  • Pallav Prakash Department of Periodontology, School of Dental Sciences, Sharda University
  • Pallavi Sharma Department of Periodontology, School of Dental Sciences, Sharda University
  • Manya Pahwa Department of Periodontology, School of Dental Sciences, Sharda University
  • Fiza Alam Department of Periodontology, School of Dental Sciences, Sharda University

Abstract

The increasing awareness of keeping oral hygiene intact and turning minds into natural therapeutic agents has become a point of concern. India, the diversified homeland to sanative herbs which can supplant harmful and delayed consequence-causing chemical substances, is a boon to the nation. Among all the phytotherapeutic essentials, lies a herb known for being all in one, pharmacological miracle - Ocimum sanctum (or commonly referred to as Tulsi). Tulsi has been applied in various arenas of medicine, especially oral medicine. The plant has immense healing potential. The chemicals extracted from the plant parts of Tulsi are emersed with analgesic, anti-inflammatory, anti-bacterial and anti-ulcerative. These properties are of significant therapeutic importance and are essential for the maintenance of oral hygiene. Apart from its favourable properties, the therapeutic agent is readily available and easy to use. Tulsi can be offered as mouthwashes, gels, irrigating agent, regenerative procedures and nanoparticles. With no harmful effects of producing stains, microbial resistance and similar efficacy to chemical agents, it can be used as an adjunctive treatment. It has shown promising outcomes in preventing tooth decay, pain, gingivitis, halitosis and periodontitis. Building up a new horizon and centre of research, Tulsi and its extravagant benefits are yet to be explored further. 

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Keywords:

Phytotherapeutic, Ocimum sanctum, electrospun nanoparticles, oral hygiene, pharmacological, herbs

Downloads

Published

2023-05-01

How to Cite

1.
Agarwal V, Warikoo A, Prakash P, Sharma P, Pahwa M, Alam F. Ocimum Sanctum: A Herbal Agent for Revivification of Periodontal Health. Scopus Indexed [Internet]. 2023 May 1 [cited 2024 Dec. 11];16(2):6445-52. Available from: https://www.ijpsnonline.com/index.php/ijpsn/article/view/3648

Issue

Section

Review Articles

References

Monga S, Dhanwal P, Kumar R, Kumar A, Chhokar V (2017). Pharmacological and physico- chemical properties of Ocimum sanctum (Ocimumgratissimum L.): An updated review. The Pharma Innovation Journal6: 181-186.

Rastogi RP, Mehrotra BN, Sinha S, Pant P, Seth R (2004). Compendium of Medicinal Plants. National Institute of Industrial Research: 320.

Jamshidi N and Cohen M M (2017). The Clinical Efficacy and Safety of Ocimum sanctum in Humans: A Systematic Review of the Literature. Evidence-Based Complementary and Alternative Medicine: 1-13.

Kadian R and Parke M (2012). Therapeutic potential and phytopharmacology of Ocimum sanctum. Int. J. of Pharm. & Life Sci. (IJPLS)3(7): 1858-1867.

Nair S K and Prasad BM S (2017). Holy Herb Ocimum sanctum as a cure for Oral and Periodontal Disease – A Review. EC Dental Science: 106-109.

Pattanayak P, Behera P, Das D and Panda SK (2010). Ocimum sanctum Linn. A reservoir plant for therapeutic applications. An overview. Pharmacognosy Review4(7): 95-105.

Kumar KPS, Bhowmik D, Biswajit, Chiranjib, Pankaj, Chandira KKTM (2010). Traditional Indian Herbal Plants Ocimum sanctum and Its Medicinal Importance. Research Journal of Pharmacognosy and Phytochemistry2(2): 103-108.

Hanumanthaiah P, Panar H, Chebte A, Haile A, Belachew GT (2020). Ocimum sanctum – a myriad plant 6(1):106-127.

Gupta D, Bhaskar DJ, Gupta RK, Karim B, Jain A, Singh R, Karim W (2014). A randomized controlled clinical trial of Ocimum sanctum and chlorhexidine mouthwash on dental plaque and gingival inflammation. J Ayurveda Integr Med 5(2): 109-16.

Gupta GD and Gaud RS (2006). Anti-inflammatory activity of Tenoxicam gel on carrageenan induced paw oedema in rats. Indian J Pharm sci 68: 356–9.

Hirasawa M, Takada K, Makimura M, Otake S (2002). Improvement of periodontal status by green tea catechin using a local delivery system: a clinical pilot study. J Periodontal Res37(6): 433-8.

Hosamane M, Acharya AB, Vij C, Trivedi D, Setty SB, Thakur SL (2014). Evaluation of Holy Basil mouthwash as an adjunctive plaque control agent in four-day plaque regrowth control. J Clin Exp Dent6(5): 4 91-96.

Nadar BG, Usha GV, Lakshminarayan N (2020). Comparative Evaluation of Efficacy of 4% Ocimumsanctum Extract, Fluoridated and Placebo Dentifrices against Gingivitis and Plaque among 14–15 years School Children in Davangere City, India – A Triple Blinded Randomized Clinical Trial. Contempt Clin Dent11(1): 67-75.

Newman and Carranza (2019); Textbook of Clinical Periodontology, 3rd South Asia Edition.

Perakath Vand Lashmanan R (2014). Ocimum sanctum-The matchless medicinal herb. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)13(2): 51- 55.

Sharma K, Acharya S, Verma E, Singhal D, Singla N (2019). Efficacy of chlorhexidine, hydrogen peroxide and Ocimum sanctum extract mouthwash in reducing halitosis using spectrophotometric analysis: A randomized controlled trial. Journal of Clinical and Experimental Dentistry11(5): 457- 463.

Newman MG, Cattabriga M, Etienne D, Flemmig T, Sanz M, Kornman KS, et al (1994). Effectiveness of adjunctive irrigation in early periodontitis. J Periodontol65 :224–9.

Cobb CM (1996). Non-surgical pocket therapy: Mechanical. Ann Periodontol1: 443–90.

Jain N, Jain GK, Javed S, Iqbal Z, Talegaonkar S, Ahmad FJ, et al (2008). Recent approaches for the treatment of periodontitis. Drug Dis Today 13: 932–43.

Matthews DC (2010). Seeing the light-the truth about soft tissue lasers and nonsurgical periodontal therapy. J Can Dent Assoc76: a30.

Natarajan PM, Mathew A, Abuhijleh E, Jaber AA, Ansari AA, Bhuvneshwari B et al (2021). Role of herbal medicine in Periodontics- A review. Sys Rev Pharm 12(1): 1611-1613.

Jayanti I, Jalauddin M, Avijeeta A, Ramanna PK, Rai PM, Nair RA (2018). In vitro Antimicrobial Activity of Ocimum sanctum extract on Aggregatibacteractinomycetemcomitans and Porphyromonasgingivalis. The Journal of Contemporary Dental Practice19(4): 415-419.

Pooja A, Nagesh L, Murlikrishnan (2010). Evaluation of the antimicrobial activity of various concentrations of Ocimum sanctum extract against Streptococcus mutans: An in vitro study. Indian J Dent Res21: 357-9.

Eley BM (1999). Antibacterial agents in the control of supragingival plaque- a review. British Dental Journal6: 286-96.

Eswar P, Devaraj CG, Agarwal P (2016). Anti-microbial activity of Ocimum sanctum extract on a periodontal pathogen in human dental plaque: An in vitro study. Journal of Clinical and Diagnostic Research10(3): 53 – 56.

Mahamood K, Yaqoob U, Bajwa R (2008). Antibacterial activity of essential oil of Ocimum sanctum (L) Mycopath6: 63-65.

Mallikarjun S, Rao A, Rajesh G, Shenoy R, Pai M (2016). Antimicrobial efficacy of Ocimum sanctum leaf extract on periodontal pathogens: An in vitro study. Journal of Indian Society of Periodontology20: 145- 50.

Singh S and Majumdar D.K (1997). Evaluation of anti-inflammatory activity of fatty acids of Ocimum sanctum fixed oil. Indian Journal of Experimental Biology35(4): 380-83.

Gattani D, Lingala S, Niswade G, Sahu J, Kar N (2019). Comparative evaluation of clinical effects of simultaneous ultrasonic scaling and irrigation with medicated water containing 2% Ocimum sanctum on gingivitis: A Clinical Intervention Study. Journal of Advanced Medical and Dental Sciences Research7(6) :93-97.

Saranya S (2016). Evaluation of the efficacy of 10% Ocimum sanctum gel as local drug delivery agent adjunct to scaling and root planning in chronic periodontitis: A randomized controlled trial: 1 – 85.

Kalsi R, Vandana KL, Prakash S (2011). Effect of local drug delivery in chronic periodontitis patients: A meta-analysis. Journal of Indian Society of Periodontology15(4): 304-9.

Rabbani GM, Ash MM Jr, Caffesse RG (1981). The effectiveness of sub gingival scaling and root planing in calculus removal. J Periodontol52(3):119-23.

Hosadurga RR, Rao SN, Edavanputhalath R, Jose J, Rompicharla NC, Shakil M et al (2015). Evaluation of the efficacy of 2% Ocimum sanctum gel in the treatment of experimental periodontitis. International Journal of Pharmaceutical Investigation5(1): 35 – 42.

Philip SA and Purushotham S (2019). Comparative Evaluation of the Efficacy of 2% Ocimum sanctum Gel and Curcumin Gel as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis: A Clinical and Microbiological Study. International Journal of Recent Scientific Research10(12): 36549-36554.

Nowzari H, MacDonald ES, Flynn J, London RM, Morrison JL, Slots J (1996). The dynamics of microbial colonization of barrier membranes for guided tissue regeneration. J Periodontol67(7): 694–702.

Mehrotra N, Palle AJ, Gadela RK, Vasudevan S (2017). Efficacy of Natural and Allopathic Antimicrobial Agents Incorporated onto Guided Tissue Regeneration Membrane Against Periodontal Pathogens: An In vitro Study. J Clin Diagn Res11(1): 84-7.

Markman C, Francakanzza SE, Novaes AB Jr, Novaes AB (1995). Slow release of tetracycline hydrochloride from a cellulose membrane used in guided tissue regeneration. J Periodontol66(11): 978-83.

Perry DA and Takei HH (2012). Phase I periodontal therapy (Newman MG, Takei HH, Klokkevold PR, Carranza FA, ed), India, pp 448-60.

Singhal G, Bhavesh R, Kasariya K, Sharma A.R, Singh R.P (2011). Biosynthesis of silver nanoparticles using Ocimum sanctum leaf extract and screening its antimicrobial activity. J Nanopart Res13(7): 2981–8.

George PM and Varghese SS (2018). ElectrospunOcimum sanctum Loaded Fiber with Potential Biomedical Applications – Periodontal Therapeutic Perspective. Biomedical & Pharmacology Journal 11(3): 1731-1736.

Bhardwaj N and Kundu SC (2010). Electrospinning: A fascinating fibre fabrication technique. Biotechnol Adv28: 325-47.

Pandey G and Madhuri S (2010). Pharmacological activities of Ocimum sanctum: A review. Int J Pharm Sci Rev Res5: 61-6.

Patel RR (2020). Ocimum sanctum: The Queen of Medicinal Herbs. J BioequivAvailab 12:407.

George PM, Jayakumar ND, Kaarthikeyan G (2021). Effectiveness of electrospun Ocimum sanctum nanofibers as an adjunct to scaling and root planning in the management of chronic periodontitis: A randomized controlled clinical trial. Journal of International Oral Health13(2): 115 -21.