Biologically Active 2,5-Disubstituted-1,3,4-Oxadiazoles

DOI:

https://doi.org/10.37285/ijpsn.2009.2.1.2

Authors

  • Harish Rajak
  • Murli Dhar Kharya
  • Pradeep Mishra

Abstract

There are vast numbers of pharmacologically active heterocyclic compounds in regular clinical use. The presence of heterocyclic structures in diverse types of compounds is strongly indicative of the profound effects such structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic drugs. The 1,3,4-oxadiazole nucleus has emerged as one of the potential pharmacophore responsible for diverse pharmacological properties. Medical Literature is flooded with reports of a variety of biological activities of 2,5-Disubstituted-1,3,4-oxadiazoles. The present work is an attempt to summarize and enlist the various reports published on biologically active 2,5-disubstituted-1,3,4-oxadiazoles.

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Keywords:

1,3,4-oxadiazoles, anti-inflammatory activity, hypoglycemic activity, anticonvulsant activity, antiallergic activity, antimicrobial activity, anticancer activity

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Published

2009-08-31

How to Cite

1.
Rajak H, Kharya MD, Mishra P. Biologically Active 2,5-Disubstituted-1,3,4-Oxadiazoles. Scopus Indexed [Internet]. 2009 Aug. 31 [cited 2024 Dec. 11];2(1):390-406. Available from: https://www.ijpsnonline.com/index.php/ijpsn/article/view/265

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